VITAMIN D3: THE NATURAL FLU BUSTER

Nature’s design of the human body is no more evident than in the function of Vitamin D. Classically considered a vitamin, it also functions much like a hormone. While chemically similar to a hormone in structure, Vitamin D is not excreted from a gland into the blood. Instead, it is miraculously synthesized in the skin from exposure to the sun. What a beautifully designed system!

Recently, I had the pleasure of interviewing Dr. Soram Khalsa on my Blog Talk radio show (http://www.blogtalkradio.com/search/dr.-howard-liebowitz/). Dr. Khalsa is a wonderful, Integrative Physician who recently published a book on Vitamin D called “The Vitamin D Revolution.” His book offers an eloquent and concise overview of the many benefits of Vitamin D as essential to an optimal health program. I wanted to summarize some of the many health benefits of Vitamin D in this post.

Vitamin D serves a variety of functions in the body. A deficiency can be associated with numerous ailments. Though rarely encountered today, the best known is rickets, a metabolic bone disease. Less well-known problems caused by Vitamin D deficiency include increased risk of heart disease, cancer, osteoporosis, osteopenia, diabetes, multiple sclerosis, autoimmune disease, flu, and depression.

Vitamin D deficiency is more common in higher latitudes especially during winter when there is less sunlight. Curiously, these sun-deprived regions also have statistically higher rates of depression, alcoholism, and even diabetes. In addition, we now have also incurred a greater rate of vitamin D deficiency disorders because of our increasing concern about sun damage skin problems such as skin cancer and aging.

The intense concern that our skin needs protection from the perceived harmful rays of the sun is responsible for contributing to many degenerative health conditions. While this approach to “skin care” serves to diminish the risk of some dermatological problems, it can create a new host of other illnesses—all related to Vitamin D deficiency. Another problem results from our industrialized society that requires us to work more indoors. This leads to people getting less sun exposure even in the lower latitudes.

Vitamin D deficiency is so common that I routinely screen all of my patients for Vitamin D levels and rarely find anyone to be in the optimum range. Studies done on children in Finland, for instance, have found 400 times higher incidences of diabetes than children in Venezuela. In one study, when Finnish children were administered 2000 IU per day of Vitamin D3, they demonstrated an eighty-percent reduction in the onset of juvenile diabetes. When pregnant women have their vitamin D levels restored to optimal levels, the incidence of juvenile diabetes was reduced 50% in their offspring.

As discussed, Vitamin D deficiency is more prevalent in winter months due to less sun exposure. This correlates exactly with the time that flu epidemics break out. Evidence supports the position that normalizing Vitamin D levels in winter will significantly reduce the incidence and number of flu cases. Vitamin D deficiency in winter is also correlated with Seasonal Affective Disorder (SAD), a type of depression.

Adequate Vitamin D is essential for preventing osteoporosis and osteopenia, which are rampant today in Westernized cultures especially after menopause. Women can significantly reduce this problem and their risk of fractures by maintaining adequate Vitamin D levels along with calcium, magnesium, strontium, and Hormone Replacement therapy. Ideal levels are between 50-100 ng/ml. This level can be maintained by simply taking a supplement of Vitamin D3 of usually 2000-5000 IU/day. Alternatively, just twenty-to-thirty minutes per day of sun exposure 
(without sun block) can accomplish the same optimal levels. However, fair skinned persons may require less than dark pigmented people, and people living closer to the equator need less exposure as well.

Vitamin D toxicity is rare due to its wide therapeutic range. Optimal dosing and monitoring is necessary by a physician who understands the importance of this essential nutrient. Further details about the wonders of Vitamin D can be obtained by reading Dr. Khalsa’s informative book.

In summary, Vitamin D is an essential and inexpensive over-the-counter, simple nutrient for preventing many serious and common ailments. Similar benefits can be achieved by regular sun exposure of well-moisturized skin and not using sunscreen.


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CALORIE RESTRICTED DIETS FOR LONGEVITY

The journal, Science, recently featured a fascinating study that has huge implications for anti-ageing and longevity medicine. The report said that rhesus monkeys who were fed a calorie-restricted diet for 20 years were two-thirds less likely to die of an age-related disease than counterparts fed on a standard diet. The risk of dying from heart disease, cancer or diabetes fell by more than two-thirds in the calorie-restricted group.

The 76 animal subjects ate 30% fewer calories. Researchers noted, “The rates of cardiovascular disease and pre-cancerous cell growth were twice as high in the control group compared with the calorie restricted group.” Furthermore, none of the calorie restricted (CR) animals became diabetic or even pre-diabetic. Brain scans were also significant and showed that the CR animals demonstrated less atrophy.

The researchers also remarked that the CR monkeys “appear to be biologically younger than the normally fed animals.’ This latest study adds to the pool of data that has been accumulating for decades supporting the low-calorie intake theory of nutrition. Going back to the 70’s, Professor Roy Walford, a researcher from UCLA, studied this theory. He was his own best subject as one of the original Biosphere scientists who lived for two years in the man-made, sealed ecological dome in the Arizona desert. Walford followed a significantly calorie-restricted diet for most of his adult life.

I remember meeting Dr. Walford in 1985 when I was working as a staff physician at the Pritikin Longevity Center in Santa Monica. We were teaching the low fat diet at that time. His approach was even more intense. Walford not only limited the percentage of fat in the diet, but the total calorie intake as well. At Pritikin, the diet we taught reflected similar calorie ranges, and was quite successful in promoting weight loss, blood pressure reduction, and reducing the need for diabetic medications. The major criticism of the diet was that it was difficult to stay on for extended periods of time.

The diet program that I teach now is similar in principle to the CR diet and is called “The Paleo Diet”. I encourage people to follow a regime that is similar to what we understand was practiced in Paleolithic times. I believe this approach works best of all for avoiding age-related diseases because we were genetically designed in that bygone era, and our success as a species was dependent on the kind of food that was available at that time.

It is highly unlikely that people during the Paleolithic period ate more than 1200 to 1800 calories per day—which is the equivalent level of the CR diet. Typical Western diets are 3000 calories per day or even more. It seems logical that lowered caloric intake would dramatically reduce the risk of age-related diseases. One of the simplest ways to accomplish this is to just cut out all man-made, dense starchy carbohydrate foods such as bread, pasta, cereal, and grains. The Paleo Diet ends up looking a lot like a CR diet as long as the target food groups are not over consumed.

A comparison of the incidence of obesity that exists today with what might have existed in Paleolithic times provides food for thought. It is safe to say that obesity simply did not exist in ancient times, and by contrast with today’s diets, is a very good indicator of how much we were originally designed to consume. Just imagine the difference between the volume of food available in today’s local supermarket as compared to what was on the Paleolithic menu. The greatest challenge for early humans had nothing to do with choice—it had everything to do with securing enough food for survival.

One of humanity’s greatest accomplishments has been the ability to produce large amounts of food to assure propagation of the species. But, this achievement has a downside and not only has been detrimental to our health and longevity, but to the environment and survival of other species. As we start out to correct our own eating problems, we must first discipline ourselves to avoid the modern tendency to overindulgence, overproduction, and overconsumption. Our well-being as an evolving species and the health of our increasingly fragile planet are both at stake.

(Thanks to Geico for the Cavemen Dining image)

NEW YORK STEM CELL SUMMIT

Last week, I was in New York City attending a Stem Cell Summit. Also attending were over 50 Stem Cell Company CEO’s from all over the world as well as a number of venture capitalists, investors, researchers, and medical practitioners. The conference, itself, was a fascinating look into what is in store for us in the future from the world of Stem Cell Therapy. In my last post, I wrote about some of the potential for Stem Cells. What is on the horizon is truly mind-boggling.

In particular, there are major developments in the areas of Orthopedics such as regenerating joint cartilage, shortening recovery time for fractures by two-thirds, and options for herniated vertebral disc sufferers. There is a tremendous amount of work also being done for Diabetes, many forms of Cancer, congestive heart failure as well as for heart attack and stroke victims. I even heard from Veterinarians who are already using stem cells for racehorses and pets with great success.

The future potential for many more health benefits is vast. All of the CEO’s present admitted that we are only just beginning to scratch the surface of what stem cells may be able to accomplish. One area I found particularly fascinating was in the regeneration of bone and cartilage in degenerated joints and fractures. Stem cells are already being used to avoid amputations in diabetics with severe peripheral vascular disease. The stem cell procedure actually helps them to grow new blood vessels, which supply blood to extremities threatened by lack of oxygen. All of the presentations focused on the thrilling work of finding cures for conditions that are currently incurable. Still, no one is even talking yet about my interest in the potential of stem cells with respect to prevention, anti-aging and life extension.

I have been working with a company called Neostem, which is a stem cell collection service. We collect stem cells from healthy, relatively young people, and then store them in a cryobank for future use. The beauty of this unique approach is that the stem cells are available on an as-needed basis. Stem cells are generally only given to the person who donated them. This is the other reason that our approach is so powerful. These stem cells are in better shape than the individual recipient because they were collected when the person was younger.

In other words, they are not used like blood donations. So, there is no risk of rejection, and since the individual will only receive his own cells, there is also no risk of transmissible disease. In a way, it is a form of “Bio-Insurance”. You can imagine that the process can provide a great sense of security when an individual knows that his stem cells are safely stored away in a cryobank if needed at some future date.

I should know. I have already put mine away and it makes me feel really good. What we are now discussing is the possibility of re-infusing them back into the donor every year or so, as a way to help maintain the equivalent, youthful age as when the cells were originally collected. I have also spoken to researchers about using them to treat women after menopause. In theory, we would inject them into the ovaries to “wake them up” as a way to start producing female hormones again. No one knows if this is possible. But, can you imagine what kind of breakthrough it represents if the procedure works?!